Motor evoked potentials (MEPs) are the electrical signals recorded from the descending motor pathways or from muscles following stimulation of motor pathways within the brain. They are used for intraoperative monitoring (IOM) to test the motor pathways.

Muscle responses are particularly affected by anesthesia and neuromuscular blockade, and special stimulation techniques and certain anesthetic regimens are used to optimize MEPs during IOM.

MEPs are used to monitor the functional integrity of the motor system during surgery.